Zinc finger libraries

Details Zinc finger libraries Zinc finger libraries

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 7/00 (2006.01) C07K 14/47 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2475276

A library of multimeric DNA binding polypeptides is provided. Preferred such polypeptides are zinc finger protein DNA binding domains. Libraries of nucleotides encoding such polypeptides, expression vectors containing such nucleotides, cells containing any of the libraries and uses of the libraries are also provided.

L'invention concerne des bibliothèques de polypeptides de liaison d'ADN multimères. Selon l'invention, des polypeptides préférés sont des domaines de liaison d'ADN de protéines en doigt de gant. L'invention concerne également des bibliothèques de nucléotides codant lesdits polypeptides, des vecteurs d'expression contenant lesdits nucléotides, des cellules contenant une des bibliothèques et des utilisations desdites bibliothèques.

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