C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/16 (2006.01) A61K 31/401 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2614193
The present invention relates to a novel crystalline form of zofenopril calcium of formula (I), chemically known as (4S)-l-[(2S)-3-(benzoylthio)-2- methylpropionyl]-4- (phenylthio)-L-proline calcium salt. The present invention further relates to a process for the preparation of the new crystalline form of zofenopril calcium and its use in pharmaceutical preparations
La présente invention concerne une nouvelle forme cristalline du zofénopril calcium de formule (I), dont le nom chimique est sel de calcium de la (4S)-1-[(2S)-3-(benzoylthio)-2-méthylpropionyl]-4-(phénylthio)-L-proline. La présente invention concerne en outre un procédé de synthèse de la nouvelle forme cristalline du zofénopril calcium ainsi que son emploi dans des préparations pharmaceutiques.
Gaikwad Avinash C.
Gore Vinayak G.
Pehere Ashok D.
Vijaykar Priyesh S.
Generics (uk) Limited
Osler Hoskin & Harcourt Llp
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