Ztnf 12, a tumor necrosis factor

Details Ztnf 12, a tumor necrosis factor Ztnf 12, a tumor necrosis factor

C - Chemistry, Metallurgy

07

K

C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2548769

Novel tumor necrosis factor ligand polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides may be used within methods relating to immune response, and may also be used in the development of immuno-regulatory therapeutics. Also provided are antibodies, binding proteins, agonists and antagonists of the ligand polypeptides.

L'invention concerne de nouveaux polypeptides de ligands du facteur de la nécrose tumorale, les polynucléotides codant les polypeptides, et des compositions et procédés associés. Les polypeptides peuvent être utilisés dans les procédés concernant la réponse immunitaire, et peuvent également être utilisés dans le développement de thérapeutiques immunorégulatrices. L'invention concerne également des anticorps, des protéines de liaison, et des agonistes et des antagonistes des polypeptides de ligands.

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