Zwitterionic bicyclic compounds and their salts, solvates,...

Details Zwitterionic bicyclic compounds and their salts, solvates,... Zwitterionic bicyclic compounds and their salts, solvates,...

C - Chemistry, Metallurgy

07

D

167/211, 260/272

C07D 471/04 (2006.01) A61K 31/435 (2006.01) C07D 215/36 (2006.01) C07D 453/02 (2006.01) C07D 519/00 (2006.01)

Patent

CA 1263654

ABSTRACT Zwitterionic bicyclic compounds are disclosed which are useful as anti-allergic, anti-inflammatory and/or cytoprotective agents. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed. The compounds have the structural formula I Image I wherein W and X may be the same or different and each independently represents -CH= or -N= ; Z1 and Z2 are the same or different and each independently represents O or S; R1 to R5 represent various organic groups; Q represents an aryl or an aromatic heterocyclic group, Y represents various substituents.

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