C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/22 (2006.01) A61K 31/195 (2006.01) A61K 31/397 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61P 25/26 (2006.01) C07C 43/196 (2006.01) C07C 51/09 (2006.01) C07C 62/34 (2006.01) C07C 217/52 (2006.01) C07C 229/46 (2006.01) C07C 229/48 (2006.01) C07D 205/04 (2006.01) C07D 207/16 (2006.01) C07D 211/34 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 241/04 (2006.01) C07D 257/04 (2006.01) C07D 265/30 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2423356
The present invention is directed to certain novel compounds represented by structural formula (I), or a pharmaceutically acceptable salt thereof, wherein R3, R5, R6, R7, R8, R11, R12, R13, Q, W, X, Y and Z are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of psychiatric disorders including depression and anxiety.
La présente invention concerne certains nouveaux composés représentés par la formule structurelle (I) ou certains de ses sels pharmaceutiquement acceptables. Dans cette formule R?3¿, R?5¿, R?6¿, R?7¿, R?8¿, R?11¿, R?12¿, R?13¿, Q, W, X, Y et Z sont tels que définis dans la description. L'invention concerne également, d'une part des formulations pharmaceutiques intégrant ces composés comme principes actifs, et d'autre part l'utilisation de ces nouveaux composés et leurs formulations pour le traitement de certains troubles. Les composés de l'invention, qui sont des antagonistes du récepteur de la tachykinine, conviennent particulièrement au traitement de troubles psychiatriques, et notamment la dépression et l'anxiété.
Finke Paul E.
Maccoss Malcolm
Meurer Laura C.
Mills Sander G.
Qi Hongbo
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Zwitterionic tachykinin receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Zwitterionic tachykinin receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Zwitterionic tachykinin receptor antagonists will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2007325