Aryl-substituted furanes, and process for their production

Details Aryl-substituted furanes, and process for their production Aryl-substituted furanes, and process for their production

C - Chemistry, Metallurgy

07

D

260/367.1, 260/3

C07D 307/42 (2006.01) C07C 45/63 (2006.01) C07C 45/71 (2006.01) C07C 59/68 (2006.01) C07D 307/54 (2006.01) C07D 307/58 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1152087

ABSTRACT OF THE DISCLOSURE Aryl substituted furanes and pharmaceutically acceptable acid addition salts thereof according to the following formula Image (I) wherein R1 and R2 may be the same or different and are selected from hydrogen, halogen, alkyl and acylamino having 1 to 4 carbon atoms, R3 and R4 may be the same or different and are selected from hydrogen and methyl, R5 is selected from hydrogen, dimethoxyphenyl and acylamino having the following formula R6 - CONH- wherein R6 is selected from alkyl having 1 to 4 carbon -1- atoms, are disclosed which are useful as anti-hyper- tensive and .beta.-adrenolytic agents. Also, substituted furanes having the formula Image (III) wherein R7 is selected from hydrogen, benzyl, the radical Image , and the radical Image , wherein X is selected from chlorine and bromine, are disclosed which are useful in the preparation of the aryl substituted furanes, Compositions containing the aryl substituted furanes, and methods of preparation are also disclosed. -2-

349334

Affiliated with

Also associated with

Rating

Aryl-substituted furanes, and process for their production does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aryl-substituted furanes, and process for their production, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl-substituted furanes, and process for their production will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1002481