Vincamine compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 519/04 (2006.01) C07D 209/16 (2006.01) C07D 461/00 (2006.01) C07D 471/14 (2006.01)

Patent

CA 1051899

VINCAMINE COMPOUNDS Abstract of the Disclosure This invention provides new compounds of formula I, Image I wherein R1 is bromine, fluorine, chlorine, hydroxyl, lower, alkyl or lower alkoxy, with the proviso that when R1 is in the 11 or 12 position, R1 is other than methoxy, and pharmaceutically acceptable acid addition salts thereof. These compounds are useful as vigilance-increasing agents.

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