Substituted pyrroloquinoxalinones and diones

Details Substituted pyrroloquinoxalinones and diones Substituted pyrroloquinoxalinones and diones

C - Chemistry, Metallurgy

07

D

260/239.4, 260/2

C07D 487/04 (2006.01) C07D 241/44 (2006.01) C07D 487/06 (2006.01)

Patent

CA 1097631

Abstract of the Disclosure This invention provides novel pyrroloquinoxali- nones and pyrrolobenzodiazepinones which are useful as anti-inflammatory and anti-thrombotic agents. These novel compounds have the formula Image I wherein R1 is hydrogen or C1-C3 alkyl; when taken singly, R2 is hydrogen, C1-C3 alkyl, C1-C3 alkoxy, chloro or fluoro, and R3 is hydrogen; or R2 and R3 when taken together with the carbon atoms to which they are attached form a benzene ring; R4 is hydrogen, chloro or fluoro; R5 is hydroxy, hydrogen or phenyl; Y is oxygen or two hydrogen atoms; Z is -CH2-CH2- or CHR6 wherein R6 is hydrogen or C1-C3 alkyl.

297309

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