Naphthyridine derivatives

Details Naphthyridine derivatives Naphthyridine derivatives

C - Chemistry, Metallurgy

07

D

260/272.5

C07D 471/06 (2006.01) C07D 471/16 (2006.01)

Patent

CA 1162544

- 16 - A B S T R A C T "NAPHTHYRIDINE DERIVATIVES" 2,3,3a,4,5,6-Hexahydro-1H-indolo[3,2,1-de]- [1,5-naphthyridine] derivatives of the general formula: Image in which R1 is in the 9- or 10-position and represents a hydrogen atom, a halogen atom or a C1-4 alkyl or C1-4 alkoxy radical and R2 represents a hydrogen atom or a C1-4 alkyl radical, are new compounds useful in therapy as they possess an anti-anoxia action and a psychotropic action. They can be prepared by reduction of the carbonyl group of corresponding 1,2,3,3a,4,5-hexahydro- 6H-indolo[3,2,1-de][1,5-naphthyridine]-6-one derivatives, which are known compounds, to methylene.

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