Methoxy-heterocyclic compounds containing aminomethyl groups

C - Chemistry – Metallurgy – 07 – D

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260/102, 260/101

C07D 501/04 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) C07D 499/00 (2006.01) C07D 501/20 (2006.01)

Patent

CA 1055924

ABSTRACT OF THE DISCLOSURE 6.beta.-Aminomethylaryl-acetylemino-6.alpha.-methoxy-2,2-dimethyl- penam-3-carboxylic acid compounds and 7.beta.-aminomethylaryl- acetylamino-7.alpha.-methoxy-3-cephem-4-carboxylic acid compounds, wherein the aminomethyl-substituted aryl radical represents a corresponding thienyl, furyl or phenyl radical, and wherein the 3-position in 3-cephem compounds is unsubstitued or substituted by a modified hydroxyl group or an optionally substituted methyl group, exhibit antibiotic actions against Gram-negative or Gram-positve micro-organisms.

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