Method and apparatus for detecting immunologic reactions by...

Details Method and apparatus for detecting immunologic reactions by... Method and apparatus for detecting immunologic reactions by...

C - Chemistry, Metallurgy

12

Q

167/37

C12Q 1/00 (2006.01) G01N 31/02 (2006.01) G01N 33/48 (2006.01)

Patent

CA 1049401

METHOD AND APPARATUS FOR DETECTING IMMUNOLOGIC REACTIONS BY DIFFUSION IN GEL Abstract of the Disclosure A thin layer of gel on a metallized solid surface has two or more wells formed through the gel which are subsequently filled with specimens of first and second solutions suspected of respectively containing first and second immunologically reactive biological particles specific to each other. The specimens are allowed to diffuse in the gel, and presence of the first and second biological particles in the solutions forms a complexed protein precipitate line on the metallized solid surface corresponding to the region of intersection of the two diffused specimens and which is visible with good contrast to the unaided eye without the need for staining the gel and provides a durable record of the immunological reaction which forms the precipitate.

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