1,4-dihydro having a basic amino-containing group attached...

Details 1,4-dihydro having a basic amino-containing group attached... 1,4-dihydro having a basic amino-containing group attached...

C - Chemistry, Metallurgy

07

D

167/211, 260/251

C07D 211/90 (2006.01) C07D 209/48 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01)

Patent

CA 1253865

ABSTRACT OF THE DISCLOSURE Novel dihydropyridines of the formula:- Image (I) and their pharmaceutically acceptable acid addition salts wherein Y is -(CH2)2-, -(CH2)3-, -CH2CH(CH3)- or -CH2C(CH3)2-; R is aryl or heteroaryl; R1 and R2 are each independently C1-C4 alkyl or 2-methoxyethyl; and R3 is hydrogen, C1-C4 alkyl, 2-(C1-C4 alkoxy)ethyl, cyclopropylmethyl, benzyl, or -(CH2)mCOR4 where m is 1, 2 or 3 and R4 is hydroxy, C1-C4 alkoxy or -NR5R6 where R5 and R6 are each independently hydrogen or C1-C4 alkyl, pharmaceutical compositions containing them, and processes for their production. The compounds are particularly useful in the treatment or prevention of a variety of cardiac conditions, e.g. angina pectoris.

423148

Affiliated with

Also associated with

Rating

1,4-dihydro having a basic amino-containing group attached... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,4-dihydro having a basic amino-containing group attached..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-dihydro having a basic amino-containing group attached... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1167846