Continuous flow metering apparatus

Details Continuous flow metering apparatus Continuous flow metering apparatus

G - Physics

05

D

50/2.1

G05D 11/00 (2006.01) G01N 1/00 (2006.01) G01N 35/08 (2006.01) G01N 33/04 (2006.01)

Patent

CA 1194316

CONTINUOUS FLOW METERING APPARATUS ABSTRACT OF THE DISCLOSURE New apparatus and methods are disclosed using liquid position sensors in conjunction with flow-stopping valves to control (meter) fluid, e.g. sample/reagent/air, aspiration into a single conduit, such as in a continuous flow system. Air or other gas separates selected ones of the liquid segments. The volume of the aspirated segment is established by sensing a flow parameter of the segmented stream of a selected one of the sensors. A pulse is generated by the sensors (detectors), for example due to the change of light intensity at a liquid- air interface traversing the conduit. The signal pulse from a sensor causes the actuation of a selected one of the valves and stops aspiration (flow) of the liquid by traversing the flow path in the conduit through an air segment. The valve cuts through air only. Therefore, the body of the valve does not contact reagent or sample liquid by this action and the risk of carryover contamination is avoided. With the aspiration cycle completed, the input end of the conduit, e.g. an aspirating probe, can consequently be immersed in different media and the cycle repeated. -1-

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