Stable antiplaque dentifrice with improved foaming and...

A - Human Necessities – 61 – K

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167/319, 167/318

A61K 8/41 (2006.01) A61K 8/44 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1238282

STABLE ANTIPLAQUE DENTIFRICE WITH IMPROVED FOAMING AND FLUORIDE STABILITY Abstract A stable antiplaque dentifrice with improved foaming and flouride chemical stability containing an antiplaque quater- nary ammonium compound, a betaine surfactant to improve foaming without inactivating the antibacterial and antiplaque activity of the quaternary ammonium compound, a humectant selected from the group consisting of polyethylene glycol, sorbitol and mixtures thereof, a nonionic gelling agent, such as hydroxy- ethylcellulose, and preferably a fluorine-containing compound capable of providing a fluoride ion,in an aqueous vehicle con- taining a dental abrasive. The sorbitol component, which stabilizes the betaine-quat system, also improves long term flouride chemical stability of the dentifrice. In a sole polyethylene glycol humectant, a small amount of glycerin, as low as l% may be utilized to improve long term fluoride stability, without adversely affecting the cosmetic stability of the dentifrice.

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