Process for the preparation of a therapeutically active...

C - Chemistry – Metallurgy – 07 – D

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260/255, 260/262

C07D 401/04 (2006.01) C07D 239/48 (2006.01) C07D 239/50 (2006.01)

Patent

CA 1268766

ABSTRACT OF THE DISCLOSURE A novel process is provided herein for the preparation of 2,4-diamino-3-oxy-6-piperidyl-pyrimidine or minoxidil. In such process, a compound of the Formula Image wherein R is a C1-4 alkyl or a phenyl group optionally having up to three C1-4 alkyl substituents, is oxidized to a compound of the Formula Image using magnesium monoperoxyphthalate or MMPP, which has the Formula Image

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