Enhanced secretion of heterologous proteins by hosts using...

Details Enhanced secretion of heterologous proteins by hosts using... Enhanced secretion of heterologous proteins by hosts using...

C - Chemistry, Metallurgy

12

N

195/1.2, 195/1.2

C12N 15/67 (2006.01) C07K 14/395 (2006.01) C07K 14/65 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/69 (2006.01) C12N 15/81 (2006.01)

Patent

CA 1318617

ABSTRACT Improved secretion of heterologous proteins by hosts such as yeast by using promoters of at most intermediate strength with heterologous DNA secretion signal sequences is disclosed. A promoter of at most intermediate strength, such as the actin (ACT) or iso-l-cytochrome c (CYCl) promoter in S. cerevisiae is operatively linked to a DNA signal sequence, such as the MF.alpha.l signal sequence. A DNA sequence for a selected protein, such as somatomedin C (SMC), tissue plasminogen activator (TPA) or tumor necrosis factor (TNF), may be operatively linked to the DNA signal sequence.

523697

Affiliated with

Also associated with

Rating

Enhanced secretion of heterologous proteins by hosts using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enhanced secretion of heterologous proteins by hosts using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enhanced secretion of heterologous proteins by hosts using... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1173584