Human nonsecretory plasmacytoid cell line

C - Chemistry – Metallurgy – 12 – N

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195/1.101

C12N 5/00 (2006.01) C07K 16/08 (2006.01) C12N 5/16 (2006.01) C12N 15/00 (2006.01)

Patent

CA 1188642

Human Nonsecretory Plasmacytoid Cell Line Abstract A human non-secretory plasmacytoid continuous cell line, established for five years in more than 150 passages, is karyotypically normal, easily grown and has the characteristic features of a plasmablast excepting for its secretory defect, and can be used for the preparation of human-human hybridomas with human B- lymphocytes and separation of the resulting hybridomas from the plasmacytoma cell line by growth in C02- containing media, or by fluorescence activated cell sorting, or both.

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