Process for producing n-acyl-hydroxy and n-acyl- acyloxy...

C - Chemistry – Metallurgy – 07 – C

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260/557, 260/579

C07C 49/825 (2006.01) C07C 103/38 (1985.01)

Patent

CA 1262144

A B S T R A C T PROCESS FOR PRODUCING N-ACYL-HYDROXY AND N-ACYL-ACYLOXY AROMATIC AMINES This invention relates to a process for producing N-acyl-hydroxy aromat-ic amines, such as N-acetyl-para-aminophenol (APAP), and N-acyl-acyloxy aromatic amines, such as 4-acetoxyacetanilide (AAA), from hydroxy aromatic ketones, such as 4-hydroxyacetophenone. Preferably the hydroxy aromatic ketones are produced from an aromatic ester, such as phenyl acetate, or from a phenolic compound, such as phenol, and an acylating agent, such as acetic acid.

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