Topical antimicrobial pharmaceutical compositions and methods

Details Topical antimicrobial pharmaceutical compositions and methods Topical antimicrobial pharmaceutical compositions and methods

A - Human Necessities

61

K

167/247, 167/255

A61K 31/23 (2006.01) A01N 37/12 (2006.01) A61K 31/20 (2006.01) A61K 31/25 (2006.01)

Patent

CA 1302280

ABSTRACT OF THE DISCLOSURE The present invention discloses a topical antimicrobial pharmaceutical composition and methods of using the same. The topical antimicrobial pharmaceutical composition includes a safe and effective amount of an ethoxylated or propoxylated glycerol fatty acid ester and a pharmaceutically acceptable carrier. Also disclosed is a topical antimicrobial pharmaceutical composition including a safe and effective amount of a tertiary mixture including, a glycerol fatty acid ester, a binary mixture of fatty acids including a first fatty acid antimicrobial agent selected from C6 to C18 fatty acids, and a second fatty acid antimicrobial agent selected from C6 to C18 fatty acids, and a pharmaceutically acceptable carrier. Further disclosed is a topical antimicrobial pharmaceutical composition including a safe and effective amount of an ethoxylated or propoxylated glycerol fatty acid ester, a binary fatty acid mixture including, a first fatty acid antimicrobial agent selected from C6 to C18 fatty acid and the second fatty acid antimicrobial agent selected from C6 to C18 fatty acids, where the second fatty acid is not the same as the first fatty acid, and a pharmaceutically acceptable carrier. Further disclosed is a method of treating and preventing microbial related skin conditions in humans or lower animals comprising topically applying, to the afflicted situs of a human of lower animal in need of such treatment, a safe and effective amount of the above composition.

533638

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