Vaccines and immunoglobulin g-containing preparations active...

A - Human Necessities – 61 – K

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A61K 39/104 (2006.01) A61K 39/40 (2006.01) C07K 14/21 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1302882

ABSTRACT OF THE DISCLOSURE: Vaccines that are active against Pseudomonas aeruginosa infections contain a single flagellar (H) antigen of serotype a or a combination of a single flagellar (H) antigen of serotype a with a flagellar (H) antigen of serotype b. Applied to man, the vaccines according to the invention induce the formation of antibodies that ate directed against any combination of partial flagellar (H) antigens a0, a1, a2, a3, a4 and b, inhibiting the motility of Pseudomonas aeruginosa pathogens and inducing the killing of the pathogens by phagocytizing cells of the human immune system.

609542

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