Platinum derivatives and cancer treatments

C - Chemistry – Metallurgy – 07 – F

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167/119, 260/60,

C07F 15/00 (2006.01) A61K 31/28 (2006.01) C07J 51/00 (2006.01)

Patent

CA 1319681

PLATINUM DERIVATIVES AND CANCER TREATMENTS ABSTRACT Derivatives of platinum group metals, particulary platinum itself, wherein the metal is linked to one or more pharmaceutically acceptable steroid, fatty acid or other lipophilic residues aiding transport of the metal across cell membranes in the body, particularly fatty acid amine or fatty acid amide groups RCH2NH- or Image where R is a hydrocarbon group, suitably or 10 to 30 carbon atoms. The derivatives are useful in the treatment of cancer.

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