Process for the preparation of 2-halogenated ergoline...

Details Process for the preparation of 2-halogenated ergoline... Process for the preparation of 2-halogenated ergoline...

C - Chemistry, Metallurgy

07

D

260/206

C07D 457/00 (2006.01) C07D 457/02 (2006.01) C07D 457/04 (2006.01) C07D 519/02 (2006.01)

Patent

CA 1301163

- 65 - PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES Abstract The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triaryl- halosilane and optionally a hydrogen halide is used. A 3999-67/MR

540700

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