Increasing labeling efficiency by forming diagnostic agent...

A - Human Necessities – 61 – K

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A61K 51/12 (2006.01) A61K 51/08 (2006.01)

Patent

CA 1235063

- 17 - ABSTRACT RADIOACTIVE DIAGNOSTIC AGENT, AND ITS PREPARATION A radioactive diagnostic agent having high labeling efficiency, prepared by bringing an aqueous solu- tion of a radioactive metallic element contaminated with a non-radioactive metallic ions into contact with a non- radioactive carrier comprising a carrier substance having a chelates-forming property and optionally a physiologically active substance chemically bonded thereto, at least one of said aqueous solution and said non-radioactive carrier comprising at least one reductive material chosen from ascorbic acid and erythrobic acid, and their salts and esters.

452757

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