Dna probe assay using neutrally charged probe strands

Details Dna probe assay using neutrally charged probe strands Dna probe assay using neutrally charged probe strands

C - Chemistry, Metallurgy

12

Q

195/1.12, 150/8.

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 1337639

A DNA probe assay is described using neutrally charged probe strands. Oligonucleotidic sequences to be detected are hybridized with these probes and the hybridized products are therefore conveniently separated from unhybridized probes on a positively charged solid phase. Unhybridized probes or the solid phase having retained the hybridized products are then analyzed to determine the presence or quantity of the oligonucleotide sequences to be detected.

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