Production of enzyme inhibitor

Details Production of enzyme inhibitor Production of enzyme inhibitor

C - Chemistry, Metallurgy

12

N

260/272, 195/122

C12N 9/99 (2006.01) C07D 455/02 (2006.01) C07D 471/04 (2006.01) C12P 17/18 (2006.01)

Patent

CA 1211733

ABSTRACT Angiotensin I converting enzyme inhibitor A-58365 factor B is provided in greater abundance than coproduced Factor A by culturing Streptomyces chromo- fuscus NRRL 15098 under submerged aerobic fermentation conditions in an aqueous nutrient culture medium sup- plement with the amino acids proline and lysine.

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