Monoclonal antibodies, to bovine serum albumin and their use...

Details Monoclonal antibodies, to bovine serum albumin and their use... Monoclonal antibodies, to bovine serum albumin and their use...

C - Chemistry, Metallurgy

12

N

167/139, 195/1.1

C12N 5/02 (2006.01) A61K 39/395 (2006.01) B01D 15/08 (2006.01) C07K 16/18 (2006.01)

Patent

CA 1235078

- 19 - ABSTRACT "Monoclonal antibodies, processes for their preparation and methods for their use" Monoclonal antibodies specific for bovine serum albumin are prepared by immunizing a mammal with bovine serum albumin to produce cells capable of producing antibodies in the body of said mammal, fusing said cells with lined myeloma cells originating from a mammal other than the immunized mammal, selecting the resultant fused cells for the production of antibodies specific for bovine serum albumin, subjecting the selected fused cells to cloning to produce monoclones, selecting the resultant monoclones for reactivity with at least one member selected from bovine serum albumin and other related albumins, culturing the selected monoclones and recovering the desired monoclonal antibody from the culture thereby obtained. Such monoclonal antibodies specific for bovine serum albumin are used in processes for isolating bovine serum albumin from a bovine serum albumin-containing material.

457413

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