Derivatives of clavulanic acid, their preparation and their use

C - Chemistry – Metallurgy – 07 – D

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C07D 498/04 (2006.01) A61K 31/43 (2006.01) C07D 257/06 (2006.01) C07D 503/00 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1175052

ABSTRACT Tetrazolyl derivatives of clavulanic acid are described, having the formula: Image wherein X is an optionally substituted tetrazolyl group attached via a nitrogen atom. These compounds are useful as antibiotics and .beta.-lactamase inhibitors.

391734

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