Antibiotic solutions and the lyophilization thereof

Details Antibiotic solutions and the lyophilization thereof Antibiotic solutions and the lyophilization thereof

A - Human Necessities

61

K

167/103.6

A61K 47/10 (2006.01) A61K 9/19 (2006.01) A61K 38/14 (2006.01) A61K 47/08 (2006.01) A61K 47/14 (2006.01)

Patent

CA 1326211

ABSTRACT Gel-free concentrated aqueous formulations of vancomycin hydrochloride are provided which comprise the antibiotic salt at a concentration between about 12% and about 50% w/v and a gel-inhibiting compound, e.g., ethanol, at a concentration between about 1% and about 20% v/v. The gel-free formulations are especially useful in a freeze-drying process for preparing vancomycin hydrochloride as a dry flowable powder in bulk or in unit-dosage form.

579735

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