Insulin-selective somatostatin analogs

Details Insulin-selective somatostatin analogs Insulin-selective somatostatin analogs

C - Chemistry, Metallurgy

12

P

195/128.2, 530/7

C12P 21/02 (2006.01) C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1333892

Anglerfish somatostatin-28 has the formula: H-Ser-Val-Asp-Ser-Thr-Asn-Asn-Leu-Pro-Pro-Arg-Glu-Arg- Lys-Ala-Gly-Cys-Lys-Asn-Phe-Tyr-Trp-Hyl-Gly-Phe-Thr-Ser- Cys-OH. Anglerfish somatostation-28 is insulin-selective when administered in vivo and is useful for the treatment of insulinoma. The 14-residue C-terminal peptide may also be used.

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