Process for the production of the pyrrolidinones having...

Details Process for the production of the pyrrolidinones having... Process for the production of the pyrrolidinones having...

C - Chemistry, Metallurgy

07

D

167/233, 260/324

C07D 207/267 (2006.01) C07C 205/51 (2006.01) C07D 207/26 (2006.01) C07D 407/06 (2006.01) C07D 409/06 (2006.01) C07F 7/10 (2006.01) C07F 9/6533 (2006.01)

Patent

CA 1249593

ABSTRACT OF THE DISCLOSURE The invention relates to novel pyrrolidinones useful for the treatment of psychic, neurological or neuromuscular disorders, of the general formula: (I) Image in which: - R1 represents hydrogen or alkyl - R2 represents alkyl, phenyl or trimethylsilyl - R3 represents 2-thienyl or a phenyl possibly substituted once or twice with halogen, methyl, methoxy or a trifluoromethyl group. The novel compounds are formed by hot cyclization of gamma amino ester of formula: Image (II) or by alkylation in the 3 position of the pyrrolidinone of formula: Image

458049

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