Carboxyalkenamidocephalosporins

Details Carboxyalkenamidocephalosporins Carboxyalkenamidocephalosporins

C - Chemistry, Metallurgy

07

D

260/100, 167/187

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 261/14 (2006.01) C07D 277/20 (2006.01) C07D 285/08 (2006.01) C07D 333/24 (2006.01) C07D 503/00 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1272713

Shionogi Seiyaku Kabushiki Kaisha CARBOXYALKENAMIDOCEPHALOSPORINS Inventor: Yoshio Hamashima - Abstract - An antibacterial 7beta-(carboxyalkenoyl)amino-3-cephem- 4-carboxylic acid represented by the following formula: Image (wherein R is aryl or a heterocyclic group; R1 is hydrogen or halogen; R2 is a single bond, alkylene, or thiaalkylene; R3 is a hydrogen atom or carboxy modifying group; R4 is hydrogen or ethoxy; R5 is hydrogen or a 3-substituent or cephalosporins; R6 is a hydrogen atom or carboxy modifying group; and X is oxygen, sulfur, or sulfinyl) a pharmaceutical composition containing the same, and a method for treating a bacterial infection with the same.

531176

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