A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/121
A61K 31/40 (2006.01) A01N 55/06 (2006.01) A61K 31/305 (2006.01) A61K 31/79 (2006.01) A61L 12/14 (2006.01)
Patent
CA 1216789
ABSTRACT OF THE DISCLOSURE METHOD OF STABILIZING THIMEROSAL IN PRESENCE OF POLYVINYLPYRROLIDONE A method of preparing solutions containing thi- merosal and polyvinylprrolidone which results in improved stability of thimerosal is disclosed. The method involves applying a certain amount of heat to the polyvinyl- pyrrolidone while it is in aqueous solution and prior to its combination with thimerosal. The required thermal input to the polyvinylpyrrolidone solution is a function of four variables: solution temperature, heating time, external pressure and polyvinylpyrrolidone concentration. Advantageously this method may be employed in the manu- facture of contact lens solutions.
455244
Huth Stanley W.
Wagner Hali G.
Gowling Lafleur Henderson Llp
Ltd. Smith Kline & French Canada
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