Substituted trans-1,2-diaminocyclohexyl amide compounds

Details Substituted trans-1,2-diaminocyclohexyl amide compounds Substituted trans-1,2-diaminocyclohexyl amide compounds

C - Chemistry, Metallurgy

07

D

167/207, 260/325

C07D 307/02 (2006.01) A61K 31/165 (2006.01) C07C 233/00 (2006.01) C07D 295/14 (2006.01)

Patent

CA 1235122

ABSTRACT OF THE DISCLOUSURE Substituted trans-1,2-diaminocyclohexyl amide compounds demonstrating selective opioid receptor binding possess utilitv as analgesic, diuretic, and psychotherapeutic agents. A method of preparing the compounds, pharmaceutical compositions employing the compounds, and a method of alleviating pain employing the compounds are also disclosed. The compounds have the general formula: (I) Image wherein R1, R2 and A are as defined in the disclosure and claims.

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