Process for the preparation of insulin derivatives

Details Process for the preparation of insulin derivatives Process for the preparation of insulin derivatives

C - Chemistry, Metallurgy

07

K

530/7.4

C07K 14/62 (2006.01)

Patent

CA 1229588

- 1 - Abstract of the disclosure: The invention relates to a process for the pre- paration of insulin derivatives of the formula I Image (I) in which R30 represents the radical of a neutral L-amino acid which can be genetically coded, X represents identical or different radicals of L-amino acids which can be genetic- ally coded, at least one of which is a basic amino acid, it being possible for the C-terminal member to be homo- serine-lactone, Y denotes Phe or H and n denotes 1, 2 or 3, by splitting of intermediates, proinsulin, preproinsu- lin or analogs thereof, which comprises carrying out the splitting reaction close to the isoelectric point of the insulin derivatives of the formula I in the presence of an aromatic hydroxy compound.

460239

Affiliated with

Also associated with

Rating

Process for the preparation of insulin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of insulin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of insulin derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1196579