Bluetongue virus vaccine, method of producing same, and...

A - Human Necessities – 61 – K

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167/130, 195/46

A61K 39/12 (2006.01) A61K 39/15 (2006.01)

Patent

CA 1226544

ABSTRACT Ruminants, particularly cattle, sheep, and goats, can be protected against bluetongue virus (BTV) infection, particularly International Serotypes IT 10, IT 11, IT 13, and IT 17, by parenteral inoculation with the vaccine of the present invention. The vaccine is prepared by attenu- ating the individual BTV serotypes in at least thirty serial passages through a continuous cell line not origi- nating from ruminants, in particular the "Vero" cell culture derived from the African Green Monkey.

418912

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