Recombinant purified protease nexin

Details Recombinant purified protease nexin Recombinant purified protease nexin

C - Chemistry, Metallurgy

12

N

530/13, 195/1.22

C12N 15/15 (2006.01) A61L 15/44 (2006.01) C07H 21/00 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339447

DNA segments encoding two slightly different protease nexin I forms (PN-I.alpha. and PN-I.beta.) are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.

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