Penetrating topical pharmaceutical compositions

Details Penetrating topical pharmaceutical compositions Penetrating topical pharmaceutical compositions

A - Human Necessities

61

K

167/159, 167/216

A61K 31/53 (2006.01) A61K 8/49 (2006.01) A61K 47/10 (2006.01) A61K 47/22 (2006.01) A61Q 7/00 (2006.01)

Patent

CA 1302269

IMPROVED PENETRATING TOPICAL PHARMACEUTICAL COMPOSITIONS ABSTRACT Topical pharmaceutical compositions containing a specific 6-amino-1,2-dihydro-1-hydroxy-2-iminopyrimidine component and a penetration-enhancing vehicle are disclosed. The vehicle com- prises a binary combination of a C3-C4 diol or C3-C6 triol and a specific C1-6 or C1-8 alcohol polar lipid compound. The vehicle provides marked transepidermal and percutaneous delivery of the iminopyrimidine compound. These compositions, when applied topicaily, act to stimulate the growth of mammalian hair on the body.

539566

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