C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/13, 167/327,
C07K 9/00 (2006.01) A61F 2/00 (2006.01) C07K 13/00 (1990.01) A61K 37/02 (1990.01) C07K 7/10 (1990.01)
Patent
CA 1296274
POLYPEPTIDE ABSTRACT OF DISCLOSURE A polypeptide having the cell-attaching activity of fibronectin. The polypeptide has 108 amino acid residues and the formula: Image Image . The polypeptide or a biologically active fragment thereof, such as Image Image Image can be employed in the preparation of substrata designed for the attachment of cells thereto. A Cys-residue may optionally be attached at the C-terminus. It can be linked to the surface of a prosthetic device to particularly attract endothelial cells and fibroblastic cells.
433833
Pierschbacher Michael D.
Ruoslahti Erkki I.
Gowling Lafleur Henderson Llp
La Jolla Cancer Research Foundation
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