3-indolecarboxamide compounds

Details 3-indolecarboxamide compounds 3-indolecarboxamide compounds

C - Chemistry, Metallurgy

07

D

260/279, 260/306

C07D 401/12 (2006.01) C07D 403/12 (2006.01)

Patent

CA 1230600

- 1 - TITLE OF THE INVENTION 3-INDOLECARBOXAMIDE COMPOUNDS ABSTRACT OF THE DISCLOSURE 3-Indolecarboxamide compounds of the formula: Image inclusive of pharmaceutically acceptable acid addition salt and/or hydrate forms thereof, wherein R1 is hydrogen or C1-4 alkyl; each of R2 and R3 is hydrogen, halogen C1-4 alkyl, C1-4 alkoxy, benzyloxy, C2-6 alkanoyloxy or hydroxy; R4 is hydrogen or C1-4 alkyl; R5 is hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy or hydroxy; R6 is hydrogen or C1-4 alkyl; X is oxygen, sulfur or direct bond; each of k and m is an integer of 1 to 3; and n is 1 or 2, are useful as drug for the pravention and treatment of various circulatory diseases.

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