Substituted imidazol¬2,1-b|quinazolin-5(3h)-ones and related...

Details Substituted imidazol¬2,1-b|quinazolin-5(3h)-ones and related... Substituted imidazol¬2,1-b|quinazolin-5(3h)-ones and related...

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

D

CPC

167/208, 260/242

IPC codes

C07D 487/04 (2006.01) A61K 31/505 (2006.01) C07D 471/14 (2006.01) C07D 487/14 (2006.01)

Type

Patent

Patent number

CA 1334294

Description

The present invention is directed to a group of imidazo[2,1-b]quinazolin-5(3H)-ones and related tricyclic compounds which have the following general formula: Image wherein R1 is H, halogen, or CH3; NR2R3 is di(lower alkyl) amino, 1-pyrrolidinyl, 1-piperidinyl, 1-homopiperidinyl, 4-methyl-1- piperazinyl, or 4-morpholinyl; and X is -CH= or -N=. These compounds are useful as bronchodilators. These compounds are prepared by the reaction of an appropriate hydrazine with an appropriate 1-substituted-2-methyl-2- imidazoline or chemically equivalent compound.

Application Number

612007

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