Chromone- and thiochromone-substituted 1,4- dihydropyridine...

Details Chromone- and thiochromone-substituted 1,4- dihydropyridine... Chromone- and thiochromone-substituted 1,4- dihydropyridine...

C - Chemistry, Metallurgy

07

D

167/211, 260/246

C07D 405/04 (2006.01) C07D 211/90 (2006.01) C07D 409/00 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1236460

ABSTRACT OF THE DISCLOSURE Dihydropyridines of the formula Image in which R1, R2, R5, R6, R7 and R8 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, an alkylene chain with 1 to 20 C atoms or an alkenylene chain with 2 to 20 atoms, the chains being optionally inter- rupted by O or S, X is O or S and Y is a direct bond, O, S, -NH- or -N- alkyl with 1 to 8 C atoms, or a pharmaceutically acceptable salt thereof, are useful as cardiotonic agents for improving heart contractility, antihypotonic agents, for lowering the blood sugar level, for detumescing mucous membranes and for influencing the salt and liquid balance.

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