C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/125, 167/243
C07D 307/935 (2006.01) C07C 45/41 (2006.01) C07D 307/937 (2006.01) C07D 317/06 (2006.01) C07D 317/30 (2006.01) C07D 319/06 (2006.01) C07D 407/00 (2006.01) C07D 407/06 (2006.01) C07F 7/18 (2006.01)
Patent
CA 1252088
ABSTRACT OF THE DISCLOSURE 5-Cyanoprostacyclins of Formula I I, Image wherein A is a -CH2-CH2-, trans-CH=CH-, or -C=C-group, W is a free or functionally modified hydroxymethylene group or a free or functionally modified Image group wherein the OH-group can be in the .alpha.- or .beta.-posi- tion, D and E together form a direct bond or D is the group , a straight-chain, sat- Image urated alkylene group of 1-5 carbon atoms, a branched, saturated or a straight-chain, unsaturated alkylene group of 2-5 carbon atoms, any of which can optionally be sub- stituted by fluorine atoms, n is the number 1, 2, or 3, E is oxygen, sulfur, a -C=C-bond, a direct bond, or a -CR4=CR5-group wherein R4 and R5 are different and can be a hydrogen atom or an alkyl group of 1-3 carbon atoms, R2 is an alkyl, cycloalkyl, optionally substituted aryl, or heterocyclic group, R1 is a free or functionally modified hydroxy group, and R3 is an acetal residue Image wherein R6, R7, R8, R9, R10 and R11 can be identical or different and each is a hydrogen atom or a straight-chain or branched alkyl group of 1-5 carbon atoms, or an unsubstituted phenyl residue, have valuable pharmacological properties.
457210
Dahl Helmut
Loge Olaf
Raduchel Bernd
Skuballa Werner
Vorbruggen Helmut
Marks & Clerk
Schering Aktiengesellschaft
LandOfFree
Prostacyclin derivatives, process for the preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Prostacyclin derivatives, process for the preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prostacyclin derivatives, process for the preparation... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1216054