Protein concentrate, method of making and method of using...

A - Human Necessities – 61 – K

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167/103.34

A61K 38/45 (2006.01) A61K 9/08 (2006.01) A61K 35/16 (2006.01) A61K 38/36 (2006.01) A61L 24/10 (2006.01)

Patent

CA 1341376

L'invention concerne un concentré de protéines coagulables par la thrombine, sa préparation et son utilisation thérapeutique. Ce concentré présente une teneur en fibrinogène supérieure à 70% et une quantité suffisante de Facteur XIII endogène. Il peut être solubilisé à température ambiante. Sa préparation fait intervenir au moins une étape de précipitation à froid l'éthanol dilué et utilise comme produit de départ le plasma total. Le concentré de l'invention permet notamment d'obtenir un fibrinogène injectable et une colle biologique de haute qualité.

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