2'-substituted-spiro[benzofuran-2(3h),1'- cycloalkanes]and...

Details 2'-substituted-spiro[benzofuran-2(3h),1'- cycloalkanes]and... 2'-substituted-spiro[benzofuran-2(3h),1'- cycloalkanes]and...

C - Chemistry, Metallurgy

07

D

260/367.1, 260/3

C07D 307/94 (2006.01)

Patent

CA 1187890

Abstract of the disclosure: 2'-Substituted-spiro/benzofuran-2(3H), 1` - cycloalkanes] and methods of preparing same are described. On the aromatic portion of the benzofuran ring, there may Le a substituent or substituents including halogen, amino,lower-alkyl-substituent amino, lower alkyl, lower alkoxy hydroxy and nitro. The sub- stituents at the 2-position of the cyclohexane ring are -(CH2) nNR1R2 where n is o, 1 or Z and R1 and R1 and R2 are each inde- pendently hydrogen and alkyl of 1-3 carbons. These compounds are useful as antidepressants and analgesics. Various other compounds which are useful as intermediates for preparing the aforementioned compounds and methods for preparing same are also described.

413653

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