Long-acting diclofenac sodium preparation

A - Human Necessities – 61 – K

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167/168, 167/260

A61K 31/195 (2006.01) A61K 9/16 (2006.01) A61K 9/36 (2006.01) A61K 9/50 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1319616

ABSTRACT OF THE DISCLOSURE A long-acting diclofenac sodium preparation is disclosed. The preparation comprises a sustained-release diclofenac sodium component which is prepared by coating a sustained-release coat onto a pharmaceutical composition comprising diclofenac sodium and an organic acid. It can decrease the maximum blood concentration of diclofenac by suppressing and controlling the rate of release of diclofenac sodium and maintain the blood concentration of diclofenac constant for a considerably long period of time. The risk of side-effect occurrences is reduced and patients are released from the obligation to take the medicine frequently.

598715

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