Derivatives of 1,2-diether-glycero-3-dicarboxylic acid...

C - Chemistry – Metallurgy – 07 – C

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260/357, 260/483

C07C 69/34 (2006.01) C07D 265/38 (2006.01) C12Q 1/34 (2006.01) C12Q 1/44 (2006.01)

Patent

CA 1285941

ABSTRACT The present invention provides a lipase substrate of the general formula:- Image wherein A is an alkylene or alkenylene radical contain- ing up to 16 carbon atoms, R and R1, which can be the same or different, each signify an alkyl, alkenyl or acyl radical containing up to 20 carbon atoms or an optionally alkyl-substituted aryl or aralkyl radical containing up to 8 carbon atoms in the alkyl moiety and wherein one of R and R1 can also be a hydrogen atom, X is the residue of an aromatic hydroxy or thiol compound, and each Y and Z, independently from each other, is -S- or -O-, Z also -CH2-. The present invention also provides a process and a reagent for the optical determination of lipase.

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