Influenza vaccine

Details Influenza vaccine Influenza vaccine

A - Human Necessities

61

K

167/130

A61K 39/145 (2006.01) C12N 7/04 (2006.01)

Patent

CA 1270438

ABSTRACT "IMPROVEMENTS RELATING TO INFLUENZA VACCINE" A T-cell inducing material comprising influenza virus nucleoprotein, useful in protecting mammals against influenza virus, is obtained by fragmentation of influenza virus. Whole virus is disrupted with detergent, preferably after preliminary treatment with a protease and the resulting nucleoprotein is separated from whole infectious virus and other materials and formulated for parenteral administration. This nucleoprotein is capable of protecting against challenge by strains of virus different from the strain from which the nucleoprotein was obtained.

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