Method for the preparation of polycyclic 1,3-thiazolidines

Details Method for the preparation of polycyclic 1,3-thiazolidines Method for the preparation of polycyclic 1,3-thiazolidines

C - Chemistry, Metallurgy

07

D

260/271, 260/264

C07D 513/04 (2006.01)

Patent

CA 1324136

ABSTRACT METHOD FOR THE PREPARATION OF POLYCYCLIC 1,3-THIAZOLIDINES A method for preparation of polycyclic 1,3- thiazolidines is described. The method comprises reacting a fluoride ion source, in a solvent, with an onium salt synthesized by the reaction of a nitrogenous heteroaromatic compound with a halomethyl trimethyl- silylmethyl sulfide, the halomethyl trimethylsilylmethyl sulfide being selected from a group consisting of chloro- methyl trimethylsilylmethyl sulfide, bromomethyl trimethyl- silylmethyl sulfide, or iodomethyl trimethylsilylmethyl sulfide.

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