C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/277.3
C07D 401/12 (2006.01) C07D 211/42 (2006.01) C07D 211/46 (2006.01) C07D 211/52 (2006.01)
Patent
CA 1193260
TITLE: N-SUBSTITUTED ANTHRANILOYLOXYALKANOATES ABSTRACT: Image I Piperidyl N-(4-quinolyl)-anthraniloyloxyalkanoates I and their pharmaceutically acceptable salts in which R = C1-C4 alkyl, (straight or branched), C2C6 alkenyl, C2C6 alkynyl, benzyl, phenethyl, 4-nitro-phenethyl or 4-amino-phenethyl; or phenacyl, benzoylethyl, .beta.-hydroxyphenethyl or ?-hydroxy-phenylpropyi, optionally substituted in the phenyl ring by one or more of a halogen atom, CF3, NO2, NH2, C1-C4 alkyl or C1-C4 alkoxy, R1 = H or phenyl R2 = H or C1-C4 alkyl R3 = H or C1-C4 alkyl one of R4 and R5 = H the other of R4 and R5 = H have analgesic and anti-inflammatory properties. They are also inhibitors of platelet aggregation and anti-depressant agents. Their preparation and pharmaceutical compositions containing them are also disclosed.
415439
Graziani Gabriele
Motta Gianni
Nardi Dante
Testa Rodolfo
Borden Ladner Gervais Llp
Recordati S.a. Chemical And Pharmaceutical Company
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