Interferon-induced human protein in pure form, monoclonal...

Details Interferon-induced human protein in pure form, monoclonal... Interferon-induced human protein in pure form, monoclonal...

C - Chemistry, Metallurgy

12

N

167/37, 195/1.1,

C12N 5/20 (2006.01) C07K 1/22 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/06 (2006.01) C12P 21/08 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340289

The invention relates to purified proteins induced in human cells by interferon .alpha. or .beta., RNAs, DNAs and hybrid vectors coding for said proteins, hosts transformed with such a hybrid vector, processes for the preparation and purification of these proteins, DNAs, vectors and hosts, monoclonal antibodies specific to these proteins, monoclonal antibody derivatives, hybridoma cell lines secreting these monoclonal antibodies, the use of the monoclonal antibodies and their derivatives in the qualitative and quantitative determination of these proteins, test kits containing the monoclonal antibodies, and pharmaceutical preparations containing said proteins. A protein of the invention shows antiviral properties ascribed to interferons and may be a valuable indicator of the cell response to an interferon therapy.

534493

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